Scientific Publications

Lyu, X.; Fan, B.; Hüser, M.; Hartout, P.; Gumbsch, T.; Faltys, M.; Merz, T. M.; Rätsch, G.; Borgwardt, K.: An empirical study on KDIGO-defined acute kidney injury prediction in the intensive care unit. Bioinformatics 40 (Suppl_1), pp. i247 - i256 (2024)

Adamer, M. F.; Brüningk, S. C.; Chen, D.; Borgwardt, K.: Biomarker identification by interpretable maximum mean discrepancy. Bioinformatics 40 (Suppl. 1), pp. i501 - i510 (2024)

Kagiou, C.; Cisneros, J. A.; Farnung, J.; Liwocha, J.; Offensperger, F.; Dong, K.; Yang, K.; Tin, G.; Horstmann, C. S.; Hinterndorfer, M. et al.; Paulo, J. A.; Scholes, N. S.; Sanchez Avila, J.; Fellner, M.; Andersch, F.; Hannich, J. T.; Zuber, J.; Kubicek, S.; Gygi, S. P.; Schulman, B. A.; Winter, G. E.: Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature Communications 15, 5409 (2024)

Webel, H.; Niu, L.; Nielsen, A. B.; Locard-Paulet, M.; Mann, M.; Jensen, L. J.; Rasmussen, S.: Imputation of label-free quantitative mass spectrometry-based proteomics data using self-supervised deep learning. Nature Communications 15 (1), 5405 (2024)

Bock, C.; Walter, J. E.; Rieck, B.; Strebel, I.; Rumora, K.; Schaefer, I.; Zellweger, M. J.; Borgwardt, K.; Müller, C.: Enhancing the diagnosis of functionally relevant coronary artery disease with machine learning. Nature Communications 15, 5034 (2024)

Van Der Byl, W.; Nussing, S.; Peters, T. J.; Ahn, A.; Li, H.; Ledergor, G.; David, E.; Koh, A. S.; Wagle, M. V.; Deguit, C. D. T. et al.; de Menezes, M. N.; Travers, A.; Sampurno, S.; Ramsbottom, K. M.; Li, R.; Kallies, A.; Beavis, P. A.; Jungmann, R.; Bastings, M. M. C.; Belz, G. T.; Goel, S.; Trapani, J. A.; Crabtree, G. R.; Chang, H. Y.; Amit, I.; Goodnow, C. C.; Luciani, F.; Parish, I. A.: The CD8+T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects. Immunity 57 (6), pp. 1324 - 1344 (2024)

Mochmann, L. H.; Treue, D.; Bockmayr, M.; Silva, P.; Zasada, C.; Mastrobuoni, G.; Bayram, S.; Forbes, M.; Jurmeister, P.; Liebig, S. et al.; Blau, O.; Schleich, K.; Splettstoesser, B.; Nordmann, T. M.; von der Heide, E. K.; Isaakidis, K.; Schulze, V.; Busch, C.; Siddiq, H.; Schlee, C.; Hester, S.; Fransecky, L.; Neumann, M.; Kempa, S.; Klauschen, F.; Baldus, C. D.: Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia. Cancer Gene Theraphy (2024)

Yi, S. A.; Sepic, S.; Schulman, B. A.; Ordureau, A.; An, H.: mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway. Molecular Cell 84 (11), pp. 2166 - 2184 (2024)

Doll, S.; Schweizer, L.; Bollwein, C.; Steiger, K.; Pfarr, N.; Walker, M.; Woertler, K.; Knebel, C.; von Eisenhart-Rothe, R.; Hartmann, W. et al.; Weichert, W.; Mann, M.; Kuhn, P. -.; Specht, K.: Proteomic Characterization of Undifferentiated Small Round Cell Sarcomas With EWSR1 and CIC::DUX4 Translocations Reveals Diverging Tumor Biology and Distinct Diagnostic Markers. Modern Pathology 37 (7), 100511 (2024)

Murgia, M.; Rittweger, J.; Reggiani, C.; Bottinelli, R.; Mann, M.; Schiaffino, S.; Narici, M. V.: Spaceflight on the ISS changed the skeletal muscle proteome of two astronauts. Npj Microgravity 10 (1), 60 (2024)

Nygaard, U.; Nielsen, A. B.; Dungu, K. H. S.; Drici, L.; Holm, M.; Ottenheijm, M. E.; Nielsen, A. B.; Glenthoj, J. P.; Schmidt, L. S.; Cortes, D. et al.; Jorgensen, I. M.; Mogensen, T. H.; Schmiegelow, K.; Mann, M.; Vissing, N. H.; Albrechtsen, N. J. B.: Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children. Communications Biology 7 (1), 688 (2024)

Chatterjee, P.; Garcia, M. A.; Cote, J. A.; Yun, K.; Legerme, G. P.; Habib, R.; Tripepi, M.; Young, C.; Kulp, D.; Dyall-Smith, M. et al.; Pohlschroder, M.: Involvement of ArlI, ArlJ, and CirA in archaeal type IV pilin-mediated motility regulation. Journal of Bacteriology 206 (6), e00089-24 (2024)

Schneider, J.; Jasnin, M.: Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography. Current Opinion in Cell Biology 88, 102356 (2024)

Gabud, R.; Lapitan, P.; Mariano, V.; Mendoza, E. R.; Pampolina, N.; Clariño, M. A. A.; Batista-Navarro, R.: Unsupervised literature mining approaches for extracting relationships pertaining to habitats and reproductive conditions of plant species. Frontiers in Artificial Intelligence 7, 1371411 (2024)

Seep, L.; Grein, S.; Splichalova, I.; Ran, D.; Mikhael, M.; Hildebrand, S.; Lauterbach, M.; Hiller, K.; Ribeiro, D. J. S.; Sieckmann, K. et al.; Kardinal, R.; Huang, H.; Yu, J.; Kallabis, S.; Behrens, J.; Till, A.; Peeva, V.; Strohmeyer, A.; Bruder, J.; Blum, T.; Soriano-Arroquia, A.; Tischer, D.; Kuellmer, K.; Li, Y.; Beyer, M.; Gellner, A.-K.; Fromme, T.; Wackerhage, H.; Klingenspor, M.; Fenske, W. K.; Scheja, L.; Meissner, F.; Schlitzer, A.; Mass, E.; Wachten, D.; Latz, E.; Pfeifer, A.; Hasenauer, J.: From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists. Scientific Data 11 (1), 524 (2024)

Wang, W.; Atherton, P.; Kreft, M.; te Molder, L.; van der Poel, S.; Hoekman, L.; Celie, P.; Joosten, R. P.; Fässler, R.; Perrakis, A. et al.; Sonnenberg, A.: Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility. Methods in Cell Science 137 (9), jcs262116 (2024)

Langer, L. M.; Kurscheidt, K.; Basquin, J.; Bonneau, F.; Iermak, I.; Basquin, C.; Conti, E.: UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2. Nucleic Acids Research, gkae323 (2024)

Rout, A. K.; Gautam, S.; Mishra, V. K.; Bopardikar, M.; Dehury, B.; Singh, H.: NMR insights into β-Lactamase activity of UVI31+Protein from Chlamydomonas reinhardtii. Journal of Magentic Resonance 362, 107689 (2024)

Nikonova, E.; Decata, J.; Canela, M.; Barz, C.; Esser, A.; Bouterwek, J.; Roy, A.; Gensler, H.; Hess, M.; Straub, T. et al.; Forne, I.; Spletter, M. L.: Bruno 1/CELF regulates splicing and cytoskeleton dynamics to ensure correct sarcomere assembly Drosophila flight muscles. PLOS Biology 22 (4), e3002575 (2024)

Horn-Ghetko, D.; Hopf, L. V. M.; Tripathi-Giesgen, I.; Du, J.; Kostrhon, S.; Tung Vu, D.; Beier, V.; Steigenberger, B.; Prabu, J. R.; Stier, L. et al.; Bruss, E. M.; Mann, M.; Xiong, Y.; Schulman, B. A.: Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature Structural & Molecular Biology (2024)