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Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. Journal of Neuroinflammation 543.
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Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 544.
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Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 545.
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Delivery of mtZFNs into Early Mouse Embryos. Methods Mol Biol 546.
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AGEpy: a Python package for computational biology. bioRxiv, p. 450890 (2018)
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Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification. Nat Cell Biol 549.
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Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD. Acta Neuropathol 550.
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TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy 552.
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Serine is the major residue for ADP-ribosylation upon DNA damage. Elife 553.
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Survival analysis with delayed entry in selected families with application to human longevity. Stat Methods Med Res 555.
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PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. The EMBO Journal 556.
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A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency. J Pathol 557.
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G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. EMBO Mol Med 558.
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Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins. Nature Communications 559.
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Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 560.
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Nucleolar Function in Lifespan Regulation. Trends Cell Biol (2018)