Research report 2023 - Max Planck Institute for Heart and Lung Research
Circadian Regulation of Cardiometabolism
Authors
Dierickx, Pieterjan; Carpenter, Bryce
Departments
CPI Forschungsgruppe „Zircadiane Rhythmik des Herzstoffwechsels“
Summary
The health of the cardiovascular system depends on its ability to respond appropriately to environmental conditions. Heart disease is increasingly associated with advanced age and impaired NAD+ metabolism, both conditions that correlate with defective/altered function of circadian rhythms. Our research into the role of NAD+ in the regulation of circadian rhythms in the ageing heart opens up new avenues for therapies for age-related heart disease.