Mysterious Meiosis

New life arises only if two healthy germ cells fuse. However, the process of meiotic cell division, essential for germ cell formation, is often faulty, or even nonfunctional - leading to miscarriages and infertility. Despite the central importance of germ cells, the cellular mechanisms by which they are formed remains mysterious. Our goal is to uncover and understand the genetic and epigenetic players that control the central processes of meiotic recombination.