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Distinct genetically-determined origins of Myd88/Bcl2-driven aggressive lymphoma rationalize targeted therapeutic intervention strategies. Blood Cancer Discov (2022)
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NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Mol Metab, S. 101626 (2022)
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Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis. Front Cell Infect Microbiol 124.
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An intermolecular hydrogen bonded network in the PRELID-TRIAP protein family plays a role in lipid sensing. Biochim Biophys Acta Proteins Proteom 125.
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Genomic Amplification of UBQLN4 Is a Prognostic and Treatment Resistance Factor. Cells 126.
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Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity. Int J Mol Sci 127.
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Monitoring the point spread function for quality control of confocal microscopes. protocols.io (2022)
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Ribosomal RACK1 Regulates the Dendritic Arborization by Repressing FMRP Activity. Int J Mol Sci 129.
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13 (1), S. 5874 (2022)
Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling. Nat Commun 130.
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Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell, S. e13725 (2022)
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119 (38), S. e2122969119 (2022)
The TOR complex controls ATP levels to regulate actin cytoskeleton dynamics in Arabidopsis. Proc Natl Acad Sci U S A 132.
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Hexosamine pathway activation improves memory but does not extend lifespan in mice. Aging Cell, S. e13711 (2022)
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Molecular inhibition of RAS signalling to target ageing and age-related health. Dis Model Mech 134.
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34 (11), S. 1875 - 1891 e7 (2022)
OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. Cell Metab 135.
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A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids. Nat Cell Biol (2022)
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Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy. Nature aging (2), S. 824 - 836 (2022)
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The fast-growing business of Serine ADP-ribosylation. DNA Repair (Amst) 138.
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The Role of GCN2 Kinase in Mediating the Effects of Amino Acids on Longevity and Feeding Behaviour in Drosophila. Front Aging 139.
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24 (1), S. 41 (2022)
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer. Breast Cancer Res 140.
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82 (14), S. 2666 - 2680 e11 (2022)
Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation. Mol Cell